Enantioselective synthesis of 2-(3 '-alkyl-2 '-carboxy cyclopropyl)glycines

Authors
Mazon, A Pedregal, C Prowse, W
Citation
A. Mazon et al., Enantioselective synthesis of 2-(3 '-alkyl-2 '-carboxy cyclopropyl)glycines, TETRAHEDRON, 55(22), 1999, pp. 7057-7064
Citations number
25
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
55
Issue
22
Year of publication
1999
Pages
7057 - 7064
Database
ISI
SICI code
0040-4020(19990528)55:22<7057:ESO2''>2.0.ZU;2-X
Abstract
New conformationally restricted glutamate analogues 2-(3'-alkyl-2'-carboxyc yclopropyl)glycines (1a-c and 2a-c) were enantioselectively prepared by the addition-elimination reaction of the chiral lithium bislactim ether anion of 3 to racemic 4-alkyl-4-bromobut-2-enoates, (C) 1999 Elsevier Science Ltd , All rights reserved.