New copper((II)) complexes of Creatinine

The importance of Creatinine in clinical chemistry is well recognized: its level in serum and urine is indicative of renal function (Creatinine Cleara nce Test) and it is the final metabolic product of Creatine, that participa tes in energy flow in the muscle tissues. It has been suggested that the me tabolism of Creatinine is connected with the complexation to metal ions. Ho wever, no thermoanalytical studies on Creatinine complexes are reported in the literature. In this work, the synthesis and the thermal behavior of new Cu-(II)-Creatinine complexes are described. By the coupled TG-FT-IR techni que, the proposed decomposition mechanism of the complexes is confirmed. A parallel characterization by solid state IR spectroscopy and mass spectrome try is also reported. Published by Elsevier Science B.V.