A pilot study of iron depletion as adjuvant therapy in chronic hepatitis Cpatients not responding to interferon

Authors
Guyader, D Boucher, E Andre, P Even, C Cottereau, J Bianchi, A Gasser, P Mendler, MH Deugnier, Y Brissot, P
Citation
D. Guyader et al., A pilot study of iron depletion as adjuvant therapy in chronic hepatitis Cpatients not responding to interferon, AM J GASTRO, 94(6), 1999, pp. 1696-1698
Citations number
7
Categorie Soggetti
Gastroenerology and Hepatology
Journal title
AMERICAN JOURNAL OF GASTROENTEROLOGY
ISSN journal
00029270 → ACNP
Volume
94
Issue
6
Year of publication
1999
Pages
1696 - 1698
Database
ISI
SICI code
0002-9270(199906)94:6<1696:APSOID>2.0.ZU;2-W
Abstract
The aim of this study was to assess the efficacy of iron depletion obtained by phlebotomy to enhance interferon response in 1 patients who had failed to respond to a standard 3-month interferon treatment. Despite a significan t effect on serum aminotransferase levels, then was no effect on viremia, a nd iron depletion was unable to trigger interferon response. (Am J Gastroen terol 1999;94:1696-1698. (C) 1999 by Am. Cell. of Gastroenterology).