We herein report 4 Japanese children who suffered epileptic seizures while
watching a popular animated TV program. They showed a photoparoxysmal respo
nse that is more frequently observed in response to rapid color (blue/red)
frame changes than monochromatic ones. These patients were all considered t
o have photosensitive epilepsy; however, chromatic sensitivity also plays a
n important role in the generation of such seizures.