Although disease- and/or treatment,lent-related changes in physical appeara
nce accompany many illnesses, the relationship of these physical changes to
appearance self-esteem and overall psychological adjustment has received l
ittle attention in the literature. In this study, subjects were 93 persons
with diagnoses of systemic sclerosis, a chronic and progressive rheumatic d
isease characterized by physical changes, especially skill thickening. Subj
ects received clinical examinations of skin tickening and provided self-rep
orts via questionnaires of their appearance-related self-esteem and overall
psychological distress. Results showed that disease-related physical chang
es were related to appearance self-esteem. Stepwise multiple regression ana
lysis found skin thickening of the right hand and fingers to be the stronge
st predictors of appearance self-esteem. Appearance self-esteem was examine
d as a possible moderator or mediator of the relationship between skin thic
kening and psychological distress. Results did not support a moderator role
for appearance self-esteem; however, appearance self-esteem met statistica
l criteria as a mediator of the relationship between skin thickening and di
stress. Interestingly, results differed for the diffuse and limited subtype
s of systemic sclerosis, suggesting that physical changes associated with d
isease may have stronger relationships with, self-esteem and overall adjadj
ustment in the context of less serious illnesses.