Signal transduction from the B cell antigen-receptor

Authors
Campbell, KS
Citation
Ks. Campbell, Signal transduction from the B cell antigen-receptor, CURR OP IM, 11(3), 1999, pp. 256-264
Citations number
74
Categorie Soggetti
Immunology
Journal title
CURRENT OPINION IN IMMUNOLOGY
ISSN journal
09527915 → ACNP
Volume
11
Issue
3
Year of publication
1999
Pages
256 - 264
Database
ISI
SICI code
0952-7915(199906)11:3<256:STFTBC>2.0.ZU;2-K
Abstract
Ligation of the B cell antigen-receptor triggers an intricate maze of inter calated biochemical events that ultimately affect B cell biological respons es; Recent advances have helped to connect many loose ends by identifying k ey adaptor proteins, such as BLNK/SLP-65, defining crucial roles for phosph atidylinositol-3-kinase and mapping pathways controlling the mitogen-activa ted protein kinases (ERK, JNK and p38).