Connexin43 mRNA and protein expression during postnatal development of defined brain regions

Authors
Aberg, ND Ronnback, L Eriksson, PS
Citation
Nd. Aberg et al., Connexin43 mRNA and protein expression during postnatal development of defined brain regions, DEV BRAIN R, 115(1), 1999, pp. 97-101
Citations number
23
Categorie Soggetti
Neurosciences & Behavoir
Journal title
DEVELOPMENTAL BRAIN RESEARCH
ISSN journal
01653806 → ACNP
Volume
115
Issue
1
Year of publication
1999
Pages
97 - 101
Database
ISI
SICI code
0165-3806(19990608)115:1<97:CMAPED>2.0.ZU;2-6
Abstract
Connexin43 (cx43) mRNA and protein were quantified in seven brain regions u sing RNase protection assays and Western blotting from postnatal day 3, 10, and 17, and adult Sprague-Dawley rats. Increases in cx43 mRNA abundance pr eceded strong increases in cx43 protein in the cerebral cortex, hippocampus , hypothalamus, and striatum, whereas smaller postnatal increases were seen in the cerebellum, brain stem, and olfactory bulbs. (C) 1999 Elsevier Scie nce B.V. All rights reserved.