Enzymatic synthesis of a branched-chain hexulose: 5-deoxy-5-C-hydroxymethyl-beta-L-xylo-hex-2-ulopyranose

Authors
David, S
Citation
S. David, Enzymatic synthesis of a branched-chain hexulose: 5-deoxy-5-C-hydroxymethyl-beta-L-xylo-hex-2-ulopyranose, EUR J ORG C, (6), 1999, pp. 1415-1420
Citations number
12
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
1434193X → ACNP
Issue
6
Year of publication
1999
Pages
1415 - 1420
Database
ISI
SICI code
1434-193X(199906):6<1415:ESOABH>2.0.ZU;2-J
Abstract
The coupling of dihydroxyacetone phosphate with 3- hydroxy-2-(hydroxymethyl )propanal (1) in the presence of rabbit muscle aldolase afforded a branched -chain hexulose phosphate isolated in 64% yield as the barium salt 3. The p arent, dephosphorylated sugar 4 was converted to its anhydro derivative 8 a nd glycoside 9.