Triorganotin compounds as antimicrobial agents

Six triorganotin derivatives of thiolupinine(1-mercaptolupinane), 2-mercapt obenzoxazole and 2-mercaptobenzothiazole were prepared and tested against s everal bacteria, fungi and protozoa. Most compounds exhibited high activity against the tested microorganisms and particularly worth noting was the ac tivity of triethyltin lupinylsulfide on Gram-negative strains. Triethylgerm anium lupinylsulfide was also prepared but was devoid of action on the whol e set of tested microorganims. (C) 1999 Elsevier Science S.A. All rights re served.