Jy. Qi et Rm. Leahy, A theoretical study of the contrast recovery and variance of MAP reconstructions from PET data, IEEE MED IM, 18(4), 1999, pp. 293-305
Citations number
37
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Eletrical & Eletronics Engineeing
We examine the spatial resolution and variance properties of PET images rec
onstructed using maximum a posteriori (MAP) or penalized-likelihood methods
. Resolution is characterized by the contrast recovery coefficient (CRC) of
the local impulse response. Simplified approximate expressions are derived
for the local impulse response CRC's and variances for each voxel, Using t
hese results we propose a practical scheme for selecting spatially variant
smoothing parameters to optimize lesion detectability through maximization
of the local CRC-to-noise ratio in the reconstructed image.