Plasma baclofen levels in children receiving continuous intrathecal baclofen infusion

Authors
Albright, AL Shultz, BL
Citation
Al. Albright et Bl. Shultz, Plasma baclofen levels in children receiving continuous intrathecal baclofen infusion, J CHILD NEU, 14(6), 1999, pp. 408-409
Citations number
10
Categorie Soggetti
Pediatrics,"Neurosciences & Behavoir
Journal title
JOURNAL OF CHILD NEUROLOGY
ISSN journal
08830738 → ACNP
Volume
14
Issue
6
Year of publication
1999
Pages
408 - 409
Database
ISI
SICI code
0883-0738(199906)14:6<408:PBLICR>2.0.ZU;2-0
Abstract
To determine the plasma baclofen concentrations of children undergoing cont inuous intrathecal baclofen infusion for treatment of cerebral spasticity, we assayed plasma samples from six children, 8 to 18 years of age, who were receiving intrathecal baclofen at constant rates of 77 to 400 mu g/day. Pl asma levels were at or below the limit of quantification (10 ng/mL) in all patients.