Inositol in concentrations of 1-4Mm (but not the control condition: mannito
l-glucose) administered in aquarium water showed enhancement of swimming ac
tivity of goldfish after acute treatment (5 hours). These data support simi
lar findings in rats. These data suggest that inositol may enhance motor ac
tivity which may be of relevance in neuropsychiatric disorders. Future stud
ies of the effects of lithium on this activity, and its potential reversal
by inositol may shed light on the possible involvement of the phosphatidyl-
inositol second messenger system in this behavior.