CYCLIC HOMOPENTAPEPTIDES .3. SYNTHETIC MODIFICATIONS TO THE CAPREOMYCINS AND TUBERACTINOMYCINS - COMPOUNDS WITH ACTIVITY AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCUS-AUREUS AND VANCOMYCIN-RESISTANT ENTEROCOCCI

Authors
LINDE RG BIRSNER NC CHANDRASEKARAN RY CLANCY J HOWE RJ LYSSIKATOS JP MACLELLAND CP MAGEE TV PETITPAS JW RAINVILLE JP SU WG VU CB WHIPPLE DA
Citation
Rg. Linde et al., CYCLIC HOMOPENTAPEPTIDES .3. SYNTHETIC MODIFICATIONS TO THE CAPREOMYCINS AND TUBERACTINOMYCINS - COMPOUNDS WITH ACTIVITY AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCUS-AUREUS AND VANCOMYCIN-RESISTANT ENTEROCOCCI, Bioorganic & medicinal chemistry letters, 7(9), 1997, pp. 1149-1152
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
9
Year of publication
1997
Pages
1149 - 1152
Database
ISI
SICI code
0960-894X(1997)7:9<1149:CH.SMT>2.0.ZU;2-8
Abstract
Modification and replacement of the beta-lysine side chain of capreomy cin and tuberactinomycin cyclic pentapeptide derivatives resulted in c ompounds with good antibacterial potency against multidrug-resistant p athogens. (C) 1997 Elsevier Science Ltd.