Chelation and fungitoxicity

This review emphasizes the importance of chelation of heterocycles (beozimi dazoles, 1,3,4-oxadiazoles, 1,3,4-thiadiazoles, 1,2,4,-triazoles and uracil s) with transition metal ions. The multifunctional heterocycles have a bett er chance to act as fungicides after chelation with metal ions or by pairin g with nucleoside bases through weak bonding in the similar way as recently reported development of drug design using metal complexes as a ligand. The work done in author's laboratory in addition to brief support taken from t he literature is discussed.