Kinetics and mechanism of alkaline hydrolysis of hydroxamic acids

Authors
Ghosh, KK Thakur, SS
Citation
Kk. Ghosh et Ss. Thakur, Kinetics and mechanism of alkaline hydrolysis of hydroxamic acids, J INDIAN CH, 76(1), 1999, pp. 28-30
Citations number
17
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF THE INDIAN CHEMICAL SOCIETY
ISSN journal
00194522 → ACNP
Volume
76
Issue
1
Year of publication
1999
Pages
28 - 30
Database
ISI
SICI code
0019-4522(199901)76:1<28:KAMOAH>2.0.ZU;2-O
Abstract
Kinetics and mechanism of the alkaline hydrolysis of N-p-tolylbenzohydroxam ic acid (p-X-C6N4(C=O)N(OH)C6H4-CH3; X = N, CH3, Cl) and its para-substitut ed methyl and chloro derivatives have been studied in 10% (v/v) aqueous dio xane at 65 degrees. Two cases of hydrolysis applicable to two different ran ges of NaOH concentrations are recognized. The relative reactivity, tempera ture, salt, solvent and solvent Isotope effects have also been examined.