A new nuclear stethoscope based on a matrix of small CdTe semiconductor det
ectors has been developed for studying the cardiac performance by gamma ven
triculography at the equilibrium in rest and stress conditions, in the earl
y and recovery phases of the coronary disease and to follow the long-term t
herapy. The light-weight probe consists of an array of 64 detectors 5 x 5 x
2 mm grouped in 16 independent units in a lead shielded aluminum box inclu
ding 16 preamplifiers. The probe is connected to an electronic box containi
ng DC power supply, 16 channel amplifiers, discriminators and counters, two
analog-triggering ECG channels, and interface to a PC. The left ventricle
activity is, preferentially, detected by using a low-resolution matching co
nvergent collimator. A physical evaluation of the probe has been performed,
both with static tests and dynamically with a hydraulic home-built model o
f bearing heart ventricle paced by a rhythm simulator. The sum of the 16 de
tectors activity provided a radiocardiogram (RCC) which well depicted the f
illing and ejection of the cardiac beats, allowing to compare the clinicall
y relevant parameters of the cardiac performance. proportional variables of
the stroke volume (SV), ejection fraction (EF) and ventricular flow-rate w
ith the known absolute values programmed on the model. The portable system
is now in operation for clinical assessment of cardiac patients. (C) 1999 E
lsevier Science B.V. All rights reserved.