Compartmental analysis revisited

Authors
Citation
A. Rescigno, Compartmental analysis revisited, PHARMAC RES, 39(6), 1999, pp. 471-478
Citations number
16
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHARMACOLOGICAL RESEARCH
ISSN journal
10436618 → ACNP
Volume
39
Issue
6
Year of publication
1999
Pages
471 - 478
Database
ISI
SICI code
1043-6618(199906)39:6<471:CAR>2.0.ZU;2-2
Abstract
This paper gives a precise definition of compartment and shows that even wh en a compartmental model is not exactly identifiable, a range of its pharma cokinetic parameters can be determined. It is thus better to know approxima te values of clearly defined parameters than exact values of quantities wit h no physical or physiological content. (C) 1999 Academic Press.