We investigate the coupled lateral-normal response to a lateral external dr
ive in a nanoscale molecular system confined between two atomically smooth
solid surfaces. We discuss the effects of shear induced dilatancy, which re
sults from the coupling, on the energy dissipation, and therefore on the fr
ictional properties. It is demonstrated that measurements of response in th
e normal direction provide additional information on the mechanisms of fric
tion and that manipulating the dilatancy opens new possibilities to control
the motion in the lateral direction. The dilatancy leads to a novel memory
effect which is amenable to experimental verification.