Estimation of skin smoothness is of ever-increasing interest especially in
the field of cosmetic research. There are some established methods for asse
ssing skin smoothness, e.g. optical and mechanical profilometry, but the pr
esentation of recently developed new methods reflects the demand for altern
atives which are more precise and practical. For fundamental research on ul
trastructure of the stratum corneum surface scanning electron microscopy is
a suitable method. A direct method is the surface evaluation of living ski
n, which is based on an optical system in a CCD camera measuring four param
eters of roughness, scaling, smoothing and wrinkling. A similar but non-dir
ect method is optical profilometry using skin replicas. Laser profilometry
produces a variety of data which can be analysed using complex mathematical
functions. A promising new method is transparency profilometry (skin visio
meter) using a very thin skin print which allows parallel light to pass thr
ough and is analysed immediately after production. The different methods ca
n be used for characterization of the skin microrelief in dermatoses or for
dynamic measurements of time-dependent changes in skin surface topography
after application of cosmetic or medical products.