Jh. Kim et al., A novel method for deprotection of N-9-phenylfluoren-9-yl group using iodine catalyst: Simple synthesis of (2S, 3R, 4R)-3,4-dihydroxyproline, SYNLETT, (5), 1999, pp. 614-616
Iodine was found to he an efficient catalyst for the deprotection of the N-
phenylfluoren-9-yl (Pf) group in tertiary amine and promote an intramolecul
ar amination. A facile and economical synthesis of (2S,3R,4R)-3,4-dihydroxy
proline was accomplished via iodine promoted cyclization and deprotection.