[3+2] cycloaddition reactions of proline benzyl ester nitrone with alkenesand alkynes

Authors
Bernotas, RC Sabol, JS Sing, L Friedrich, D
Citation
Rc. Bernotas et al., [3+2] cycloaddition reactions of proline benzyl ester nitrone with alkenesand alkynes, SYNLETT, (5), 1999, pp. 653-655
Citations number
16
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
5
Year of publication
1999
Pages
653 - 655
Database
ISI
SICI code
0936-5214(199905):5<653:[CROPB>2.0.ZU;2-P
Abstract
Proline-based nitrone 2a has been synthesized. It readily underwent [3+2] c ycloadditions with a variety of alkene and alkyne substrates to give isoxaz olidines and isoxazolines, respectively, with good to excellent regio- and diastereoselectivity.