A fresh AIR synthesis

Authors
Humphries, MJ Ramsden, CA
Citation
Mj. Humphries et Ca. Ramsden, A fresh AIR synthesis, SYNTHESIS-S, (6), 1999, pp. 985-992
Citations number
26
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
6
Year of publication
1999
Pages
985 - 992
Database
ISI
SICI code
0039-7881(199906):6<985:AFAS>2.0.ZU;2-2
Abstract
Two short synthetic routes to the biosynthetic purine precursor 5-aminoimid azole ribonucleotide (AIR) based on catalytic reduction of 5-nitroimidazole s are described. The synthetic ribonucleoside AIRs, which is also available via one of these routes, is a convenient intermediate for the synthesis of nucleoside analogues acid preparations of the novel "pyridine-stretched'' analogues of adenosine and inosine are described.