(E)-1,2-bis(5-aryl-1,3,4-oxadiazol-2-yl)ethenes

Citation
H. Detert et D. Schollmeier, (E)-1,2-bis(5-aryl-1,3,4-oxadiazol-2-yl)ethenes, SYNTHESIS-S, (6), 1999, pp. 999-1004
Citations number
26
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
6
Year of publication
1999
Pages
999 - 1004
Database
ISI
SICI code
0039-7881(199906):6<999:(>2.0.ZU;2-H
Abstract
A series of(E)-1,2-bis(1,3,4-oxadiazol-2-yl)ethenes with a variety of aroma tic substituents in the 5-positions of the heterocycles was prepared by acy lation of the corresponding tetrazoles with fumaryl chloride and subsequent thermal ring transformation. The modified Huisgen reaction renders a new p athway to 3-(1,3,4-oxadiazol-2-yl)propenoic acids and subsequently to the t itle compounds with different substituents.