Heliannuol E. A novel bioactive sesquiterpene of the heliannane family

Authors
Macias, FA Varela, RM Torres, A Molinillo, JMG
Citation
Fa. Macias et al., Heliannuol E. A novel bioactive sesquiterpene of the heliannane family, TETRAHEDR L, 40(25), 1999, pp. 4725-4728
Citations number
33
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
25
Year of publication
1999
Pages
4725 - 4728
Database
ISI
SICI code
0040-4039(19990618)40:25<4725:HEANBS>2.0.ZU;2-0
Abstract
From the medium polar active fractions of leaf aqueous extracts of Helianth us annuus L. cv. SH-222, we have isolated heliannuol E (1) which contains a previously unknown six-membered ring containing bicyclic skeleton. The str uctural elucidation is based on extensive spectral studies, including H-1-H -1 COSY, H-1-C-13 HETCOR, and NOE difference experiments. (C) 1999 Elsevier Science Ltd. All rights reserved.