A null HLA-A*68 allele in a bone marrow donor

Authors
Laforet, M Froelich, N Parissiadis, A Schell, A Pfeiffer, B Cazenave, JP Tongio, MM
Citation
M. Laforet et al., A null HLA-A*68 allele in a bone marrow donor, TISSUE ANTI, 53(6), 1999, pp. 573-575
Citations number
6
Categorie Soggetti
Medical Research Diagnosis & Treatment
Journal title
TISSUE ANTIGENS
ISSN journal
00012815 → ACNP
Volume
53
Issue
6
Year of publication
1999
Pages
573 - 575
Database
ISI
SICI code
0001-2815(199906)53:6<573:ANHAIA>2.0.ZU;2-R
Abstract
The authors describe an A*68 allele present at the molecular level but not expressed at the cell surface. This non expression results from the deletio n of one nucleotide in exon 1, which causes a shift of the reading frame le ading to an early non-sense codon in the same exon.