Anaplastic large cell lymphoma (ALCL) is a high-grade non-Hodgkin's lymphom
a recognized by the expression of the CD30 marker and by its morphology. We
report an unusual case of ALCL in a 42-year-old woman. For ten years the p
atient only had pruritic erythematous skin lesions, then a plaque with nodu
les and ulcers on the right thigh and leg developed, followed by ichthyosis
acquisita. The development of ALCL in women and the association of ichthyo
sis acquisita with this type of lymphoma are uncommon.