Blood transfusion and risk of non-Hodgkin's lymphoma

A few epidemiologic studies have suggested that blood transfusion may be a risk factor for non-Hodgkin's lymphoma, The authors tested this hypothesis in a population-based, case-control study, using pathologically verified no n-Hodgkin's lymphoma cases and transfusion documented via medical records, In 221 age- and sex-matched case-control pairs from Olmsted County, Minneso ta, in 1975-1993, the authors observed an odds ratio of 0.84 (95% confidenc e interval 0.50-1.41) for history of transfusion and non-Hodgkin's lymphoma . There also was no apparent association between transfusion and non-Hodgki n's lymphoma in any subgroup analysis. Results do not support the hypothesi s that blood transfusion contributes to the occurrence of non-Hodgkin's lym phoma.