Kinetic spectrophotometric method for the analysis of methyldopa

Citation
Mih. Helaleh et al., Kinetic spectrophotometric method for the analysis of methyldopa, AN QUIM-INT, 94(4-5), 1998, pp. 354-356
Citations number
9
Categorie Soggetti
Chemistry
Journal title
ANALES DE QUIMICA-INTERNATIONAL EDITION
ISSN journal
11302283 → ACNP
Volume
94
Issue
4-5
Year of publication
1998
Pages
354 - 356
Database
ISI
SICI code
1130-2283(1998)94:4-5<354:KSMFTA>2.0.ZU;2-6
Abstract
A simple and accurate method for the analysis of methyldopa, using differen tial method is described. The spectrophotometric measurements were recorded by measuring the increase in absorbance at 310 nm and 470 nm after reactin g methyldopa with potassium iodate at 30 +/- 1 degrees C. The kinetic param eters were calculated. The concentration range was valid from 125-750 ppm a nd the molar absorptivities were 0.69x10(2) and 0.2x10(2) L mol cm(-1) at 3 10 and 470 nm respectively. The proposed kinetic method has been applied su ccessfully to formulation. The results obtained in the present work have be en statistically compared with reference method.