We present a case of splenic infarction in pregnancy secondary to acute bac
terial endocarditis, Left upper quadrant pain in pregnancy can be due to a
variety of causes and in the septic or unwell patient, splenic infarct shou
ld be considered in the differential diagnosis. The diagnosis of splenic in
farct should be considered especially in those at increased risk of bacteri
al endocarditis. Acute bacterial endocarditis can occur even in patients wi
thout any risk factors, Bacterial endocarditis is rare in pregnancy and spl
enic infarction is even rarer. How ever when it occurs, rapid diagnosis and
management are necessary to minimize embolic phenomena. With the increasin
g use of intravenous drugs and with increasing numbers of Pacific Islanders
in our pregnant population, it is important to be alert to the risk of bac
terial endocarditis and to avoid serious sequelae. Patient education to the
importance of medical follow-up in order to prevent such a life-threatenin
g condition, and to avoid more complicated acute treatment, is imperative.