Neuroimmune interactions in systemic rheumatic diseases were studied. The s
tate of the central. nervous system was assessed from the parameters of con
stant brain potentials, and the state of the immune system, from a complex
of immunobiochemical parameters. The highest multiple correlation coefficie
nts were revealed between the immunobiochemical parameters and the paramete
rs of the constant brain potential, which characterize linear and standard
deviations of potentials in temporal zones from potentials at other points
of recording. The results are discussed in terms of structural and function
al integration of the immune and nervous systems.