Constant brain potentials as neurophysiological markers of the autoimmune process

Neuroimmune interactions in systemic rheumatic diseases were studied. The s tate of the central. nervous system was assessed from the parameters of con stant brain potentials, and the state of the immune system, from a complex of immunobiochemical parameters. The highest multiple correlation coefficie nts were revealed between the immunobiochemical parameters and the paramete rs of the constant brain potential, which characterize linear and standard deviations of potentials in temporal zones from potentials at other points of recording. The results are discussed in terms of structural and function al integration of the immune and nervous systems.