D. Subrahmanyam et al., Novel C-ring analogues of 20(S)-camptothecin-Part-2: Synthesis and in vitro cytotoxicity of 5-C-substituted 20(S)-camptothecin analogues, BIOORG MED, 9(12), 1999, pp. 1633-1638
A series of 5-C-substituted 20(S)-camptothecin analogues were synthesised a
nd evaluated their in vitro anti-cancer activity. Several of these analogue
s have showed excellent activity against human tumor cell lines. (C) 1999 E
lsevier Science Ltd. All rights reserved.