Landomycin A inhibits DNA synthesis and G(1)/S cell cycle progression

Authors
Crow, RT Rosenbaum, B Smith, R Guo, Y Ramos, KS Sulikowski, GA
Citation
Rt. Crow et al., Landomycin A inhibits DNA synthesis and G(1)/S cell cycle progression, BIOORG MED, 9(12), 1999, pp. 1663-1666
Citations number
9
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
9
Issue
12
Year of publication
1999
Pages
1663 - 1666
Database
ISI
SICI code
0960-894X(19990621)9:12<1663:LAIDSA>2.0.ZU;2-Y
Abstract
Landomycin A was found to inhibit the uptake of [H-3]thymidine into DNA in murine smooth muscle cells indicating decreased DNA synthesis. Subsequent s tudies showed that landomycin A inhibits cell cycle progression. (C) 1999 E lsevier Science Ltd. All rights reserved.