Oxidative stress: Protein folding with a novel redox switch

Authors
Ruddock, LW Klappa, P
Citation
Lw. Ruddock et P. Klappa, Oxidative stress: Protein folding with a novel redox switch, CURR BIOL, 9(11), 1999, pp. R400-R402
Citations number
11
Categorie Soggetti
Experimental Biology
Journal title
CURRENT BIOLOGY
ISSN journal
09609822 → ACNP
Volume
9
Issue
11
Year of publication
1999
Pages
R400 - R402
Database
ISI
SICI code
0960-9822(19990603)9:11<R400:OSPFWA>2.0.ZU;2-9
Abstract
A novel cellular response to oxidative stress has been discovered, in which the activity of a molecular chaperone, Hsp33, is modulated by the environm ental redox potential. This provides a rapid first defence mechanism agains t the potentially very harmful toxic effects of oxidative stress.