Angiocentric lymphoma involving the temporal bone in a child

Involvement of the temporal bone in patients with malignant lymphomas is ve ry rare. Most of the reported cases have been clinically asymptomatic and w ere diagnosed only by post-mortem examinations. We present a nasal, paranas al, nasopharyngeal lymphoma that occurred in a 12-year-old child and also i nvolved the temporal bone. Clinical presentation began with bilateral chron ic otitis media. Histopathologically, tumor was found to be an angiocentric lymphoma of B-cell origin. Association with Epstein-Barr virus could not b e demonstrated. Despite combination chemotherapy (with cyclophosphamide, vi ncristine, doksorubicine, prednisolone, L-asparaginase, cytosine arabinosid e, metotraxate) and radiotherapy (to 40 Gy), disease progressed locally as well as to cervical lymph nodes and the lungs.