Water-containing terrestrial, subterranean and submarine high temperature a
reas harbor a variety of hyperthermophilic bacteria and archaea which are a
ble to grow optimally above 80 degrees C. Hyperthermophiles are adapted to
hot environments by their physiological and nutritional requirements. As a
consequence, cell components like proteins, nucleic acids and membranes hav
e to be stable and even function best at temperatures around 100 degrees C.
The chemolithoautotrophic archaeon Pyrolobus fumarii is able to grow at 11
3 degrees C and, therefore, represents the upper temperature border of life
. For the first time, (vegetative) cultures of Pyrolobus and Pyrodictium ar
e able to survive autoclaving. (C) 1999 Federation of European Biochemical
Societies.