LOW-LEVELS OF SERUM-SOLUBLE C-KIT RELATES TO DELAYED ENGRAFTMENT AFTER BONE-MARROW TRANSPLANTATION

Authors
HASHINO S IMAMURA M TANAKA J KOBAYASHI S KASAI M SAKURADA K ASAKA M
Citation
S. Hashino et al., LOW-LEVELS OF SERUM-SOLUBLE C-KIT RELATES TO DELAYED ENGRAFTMENT AFTER BONE-MARROW TRANSPLANTATION, Leukemia & lymphoma, 25(3-4), 1997, pp. 327-331
Citations number
13
Categorie Soggetti
Hematology
Journal title
Leukemia & lymphoma → ACNP
ISSN journal
10428194
Volume
25
Issue
3-4
Year of publication
1997
Pages
327 - 331
Database
ISI
SICI code
1042-8194(1997)25:3-4<327:LOSCRT>2.0.ZU;2-8
Abstract
Serum soluble c-kit concentrations were measured in 28 patients underg oing bone marrow transplantation (BRIT). The c-kit levels in patients with delayed engraftment (time to leukocyte recovery >1.0 x 10(9)/L be ing more than 20 days after BMT) were significantly lower than those i n patients with early engraftment (time to leukocyte recovery being le ss than 19 days after BMT) from the start of conditioning until day 10 0 after BMT. The data from this study indicates that the measurement o f serum soluble c-kit concentrations may be a useful indicator of engr aftment.