The physician B. Adamantiades and his contribution to the disease Adamantiades-Behcet

Adamantiades-Behcet disease is a multifocal entity which was first describe d by Hippocrates 500 years BC. The disease is characterised by relapsing oral aphthae, genital ulcers and iritis, while 24-40% of cases present with arterial or venous thromboses, a rterial aneurysms or varices. In rare cases, due to invasion of different s ystems, the clinical picture varies, making timely diagnosis difficult. The disease is common all over the world but is more frequent in Japan, Korea, China and the Middle East. The first description in contemporary times was made by the Creek ophthalmologist Benedict Adamantiades in 1931, and the d isease was described for the second time, independently, by the Turkish der matologist Hulusi Behcet in 1937.