Osteo-neuro-meningo-lombosacreal involvement in Marfan syndrome: one case.

Marfan syndrome is an hereditary condition which primarily affects conjunct ive tissue with predominant vascular lesions, aortic insufficiency and aort ic dissection which condition vital prognosis. Until further progress is ma de in the genetic determination of the disease, the diagnosis is currently based on the association of clinical criteria, which enables multidisciplin ary management. This approach should lead to specific medical and surgical treatment-which may reduce Marfan morbidity and mortality. We report the ca se of a 45 pear-old patient with suspected Marfan syndrome during adolescen ce. The presence of a cardiovascular lesion and a recently reported abnorma lity ie a sacral erosion by a dural ectasia, enabled us to confirm the diag nosis. We reviewed the current criteria in Marfan diagnosis and their speci fic management.