Surveys of sexual behavior in autism suggest a variety of behavioral expres
sion. However, the course of sexual development in autism is unplotted, lea
ving questions about the normalcy of specific behaviors. Even less is known
about deviations of sexual development and the incidence of paraphilias in
this population. We explore the problems of definition of sexual behaviors
and describe a case report that highlights the difficulties of management.
An application of a testosterone-suppressing medication and its effect on
sexual behavior are reported. After failure of behavioral and educational p
rograms, leuprolide, an injectable antiandrogen, resulted in suppression of
behaviors and retention of the participants' community placement. Follow-u
p for almost 3 years shows no abnormal physical effects. Dosage has been ta
pered over that period to a low but effective dose. Directions for research
are discussed.