Aims-To identify the number and type of infections occurring in United King
dom clinical laboratories during 1994 and 1995, following similar surveys c
overing 1970 to 1989.
Methods-A retrospective questionnaire survey was undertaken of 397 respondi
ng UK clinical laboratories covering 1994 and 1995. A follow up telephone s
urvey was undertaken with each of the laboratories from which a questionnai
re had been received indicating a possible or probable laboratory acquired
infection during 1994 or 1995.
Results-Questionnaires were sent to 659 laboratories or organisations which
were thought to have laboratories, of which 557 responded (response rate o
f 84.5%). Of these, only 397 were from organisations with laboratories. Ove
r 55 000 person-years of occupational exposure were covered, and only nine
cases identified, giving an infection incidence rate overall of 16,2/100 00
0 person-years, compared with 82.7 infections/100 000 person-years found in
a similar survey covering 1988 and 1989, reported previously. Infections w
ere commonest in females, in relatively young staff, in microbiology labora
tory workers, and in scientific/technical employees. Gastrointestinal infec
tions predominated, particularly shigellosis, but few specific aetiological
factors relating to working practices were identified. No hepatitis B case
s were reported.
Conclusions-The small number of cases identified indicates high standards o
f infection control, though there is still room for improvement. Periodic s
tudies of this kind are not adequate for comprehensive monitoring of the in
cidence of laboratory acquired infections. That will require the introducti
on of a routine, active surveillance programme or prospective survey which
has the support and commitment of the laboratories themselves.