It remains controversial whether patients with gallstones with acute cholec
ystitis should be operated on early, or whether surgery should be delayed u
ntil the acute phase subsides. To help resolve this question, we retrospect
ively studied 109 patients with acute cholecystitis, 56 of whom underwent l
aparoscopic cholecystectomy after acute cholecystitis had subsided (delayed
group) and 53 of whom underwent early laparoscopic cholecystectomy-within
7 days after admission (early group). On admission, the inflammatory findin
gs in the two groups were very similar; however, at operation, the inflamma
tory findings were alleviated in the delayed group, while they remained unc
hanged in the early group. The mean operative time for the two groups was v
ery similar. As for intraoperative complications, there was no conversion t
o laparotomy in either group, and there were no major complications in eith
er group. The total hospital stay was 37.7 +/- 14.4 days for the delayed gr
oup and 12.7 +/- 2.0 days for the early group, showing a highly significant
difference (P < 0.001). Early laparoscopic cholecystectomy seems to be bet
ter than delayed treatment for patients with gallstones with acute cholecys
titis.