Excretion of biotrace elements using the multitracer technique in mice

A radioactive multitracer solution obtained from the nuclear reaction of se lenium with 25 MeV/nucleon Ar-40 ions was applied to the investigation of t he trace elements behavior in feces and urine of mouse. The excretion rates of 23 elements, Na, K, Rb, Mg, Ca,Sr, Ga, As, Sc, V, Cr, Mn, Co, Fe, Zn, Y , Zr, Mo, Nb, Tc, Ru, Ag and In were simultaneously detected under strictly identical experimental conditions, in order to clarify the excretion behav ior of the elements in mice. Fecal and urinary excretion rates of the eleme nts in mice reached the highest value separately at 48 and 23 hours. The to tal excretion of Mo,Tc and Co within 96 hours were all larger, more than 60 %. Accumulative excretion rates of Ca, Nb, Mg, Sr, V, Sc, Na Cr. Fe, Ag, Mn and Zr were 60-30%. The total rates of Ru, K, As, Zn, Rb, Y, Ga and In wer e less than 30%, and low excretion. The main excretion pathway of Mo, Co, M g, Fe and Ag was through urine, and Na, K, As and Rb were eliminated from t he body also in urine. But fecal excretion of Tc, Nb, Sr, Y, Ru, and In wer e larger than urinary excretion, and Ca, Sc, Mn, Zr, Zn were eliminated fro m the body in feces.