Objective: The purpose of high-risk studies is to find characteristics that
allow the identification of subjects with a higher vulnerability to alcoho
lism. The aim of this research was to verify if the familial density criter
ion is useful for subtyping children of alcoholics with different neuropsyc
hological characteristics. Method: A battery of neuropsychological tests wa
s administered to 102 boys and girls of 7-15 years of age; 66 were children
of alcoholics with a high (n = 32) and low (n = 34) familial density of al
coholism, and 36 were children of nonalcoholic fathers with a negative fami
ly history of the disorder. The battery included tests to assess attention,
visuospatial abilities and frontal functions. Results: MANCOVAs showed tha
t high-density children scored lower than children of nonalcoholic fathers
in attentional and visuospatial tasks. There were no differences between lo
w-density and negative family history children in these cognitive domains.
Conclusions: These results suggest that children of alcoholics are not a ho
mogeneous group. Children with multigenerational alcoholism, but not childr
en with an alcoholic father, showed reduced performance in specific cogniti
ve areas.