Instantons are the natural mechanism in non-perturbative QCD to remove heli
city from valence quarks and transfer it to gluons and quark-antiquark pair
s. To understand the extent to which instantons explain the so-called "spin
crisis" in the nucleon, we calculate moments of spin-dependent structure f
unctions in quenched QCD and compare them with the results obtained with co
oled configurations from which essentially all gluon contributions except i
nstantons have been removed. Preliminary results are presented.