Extremely high enantioselective redox reaction of ketones and alcohols catalyzed by RuCl2(PPh3)(oxazolinylferrocenylphosphine)

Authors
Nishibayashi, Y Takei, I Uemura, S Hidai, M
Citation
Y. Nishibayashi et al., Extremely high enantioselective redox reaction of ketones and alcohols catalyzed by RuCl2(PPh3)(oxazolinylferrocenylphosphine), ORGANOMETAL, 18(12), 1999, pp. 2291-2293
Citations number
41
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANOMETALLICS
ISSN journal
02767333 → ACNP
Volume
18
Issue
12
Year of publication
1999
Pages
2291 - 2293
Database
ISI
SICI code
0276-7333(19990607)18:12<2291:EHERRO>2.0.ZU;2-O
Abstract
The ruthenium complex RuCl2(PPh3)(oxazolinylferrocenylphosphine), 1, has be en found to be a quite effective catalyst for asymmetric transfer hydrogena tion of not only alkyl aryl ketones but also alkyl methyl ketones with (PrO H)-Pr-i. Asymmetric oxidation of racemic sec-alcohols with acetone via kine tic resolution by using the same catalyst 1 also proceeds with exteremely h igh enantioselectivity (>99.9% ee).