Comparative study on the in vitro antibacterial activity of Australian teatree oil, cajuput oil, niaouli oil, manuka oil, kanuka oil, and eucalyptusoil
M. Harkenthal et al., Comparative study on the in vitro antibacterial activity of Australian teatree oil, cajuput oil, niaouli oil, manuka oil, kanuka oil, and eucalyptusoil, PHARMAZIE, 54(6), 1999, pp. 460-463
To compare the antibacterial activity of the Australian tea tree oil (TTO)
with various other medicinally and commercially important essential myrtace
ous oils(cajuput oil, niaouli oil, kanuka oil, manuka oil, and eucalyptus o
il) the essential oils were first analysed by GC-MS and then tested against
various bacteria using a broth microdilution method. The highest activity
was obtained by TTO, with MIC values of 0.25% for Enterobacter aerogenes, E
scherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Salmonella chole
raesuis, Shigella flexneri, Bacillus subtilis, Listeria monocytogenes, Stap
hylococcus aureus, S. saprophyticus, and S. xylosus. It is noteworthy that
manuka oil exhibited a higher activity than TTO against gram-positive bacte
ria, with MIC values of 0.12%. Both TTO and manuka oil also demonstrated a
very good antimicrobial efficacy against various antibiotic-resistant Staph
ylococcus species. Pseudomonas aeruginosa was resistant to all essential oi
ls tested, even at the highest concentration of 4%.