Transition metal compound mediated reduction of alpha-amino acids to 1,2-amino alcohols with NaBH4 in water

Authors
Demir, AS Akhmedov, IM Sesenoglu, O
Citation
As. Demir et al., Transition metal compound mediated reduction of alpha-amino acids to 1,2-amino alcohols with NaBH4 in water, TURK J CHEM, 23(2), 1999, pp. 123-126
Citations number
24
Categorie Soggetti
Chemistry
Journal title
TURKISH JOURNAL OF CHEMISTRY
ISSN journal
13000527 → ACNP
Volume
23
Issue
2
Year of publication
1999
Pages
123 - 126
Database
ISI
SICI code
1300-0527(1999)23:2<123:TMCMRO>2.0.ZU;2-5
Abstract
A new efficient and cost-effective method for the preparation of 1,2-amino alcohols is described. The reactions of amino acids with NaBH4 in the prese nce of NiCl2 or MoO3 in water give 1,2-amino alcohols in high yield. When o ptically pure amino acids were used, optically pure 1,2-amino alcohols were obtained.