XLMR database

The computer database on X-linked mental retardation (MMR) disorders develo ped by Arena and Lubs in 1991 has now been updated to include all currently known XLMR disorders and nonspecific (MRX) families. Currently, it include s 123 syndromes, 59 nonspecific XLMR families, and 60 families from the Mia mi/Greenwood study. The older clinical reports have been reviewed and revis ed. The search mechanism has also been revised and now includes 740 individ ual "keywords." Each of these keywords recognizes several of clinical descr iptive terms, as used in published literature reports. Searches can be made according to any clinical finding or combination of findings. For each dis order, the database presents a, graphic display that contains a revised and more complete set of clinical findings, references, keywords, map localiza tion, molecular information, access to pictures, and OMIM number. Am. J. Me d. Genet. 85:202-205, 1999. (C) 1999 Wiley-Liss, Inc.