The rotary blood pump will be widely used in the near future as an implanta
ble left ventricular assist device (LVAD). However, one obstacle for the ce
ntrifugal pump is a control method that can maintain an optimum flow rate i
n a physiological condition. Thus, the object of this study is to develop t
his optimum control system for the centrifugal pump. If the heart function
and pump efficiency are stable, the ratio of the systole current to the the
diastole current (S/D) will be a fixed value. However, if the heart functi
on and pump efficiency are unstable, S/D will not be a fixed value. This co
ntrol system was investigated with a calf that was subjected to an ex vivo
LVAD study. The LVAD was a Gyro C1E3 centrifugal pump. The pump flow rate w
as changed to 1.5, 3.5, 5.2, and 6.2 L/min. According to the changes of the
pump flow rates, the S/D values were 1.01 +/- 0.01, 1.06 +/- 0.05, 1.03 +/
- 0.01, and 1.03 +/- 0.01, respectively. There was no statistical differenc
e among the 3 groups. In a separate experiment, the backflow condition S/D
was 1.88 +/- 0.6, and the normal condition S/D was 1.35 +/- 0.5. There was
a statistical difference between the 2 groups. The results of this study su
ggest that S/D is not influenced by the pump flow rate, However, the S/D wa
s changed when the pump was in a backflow condition. This method will be us
eful in controlling a centrifugal pump requiring only electrical current in
formation.