Synthesis and identification of conformationally constrained selective MMPinhibitors

Authors
Freskos, JN McDonald, JJ Mischke, BV Mullins, PB Shieh, HS Stegeman, RA Stevens, AM
Citation
Jn. Freskos et al., Synthesis and identification of conformationally constrained selective MMPinhibitors, BIOORG MED, 9(13), 1999, pp. 1757-1760
Citations number
6
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
9
Issue
13
Year of publication
1999
Pages
1757 - 1760
Database
ISI
SICI code
0960-894X(19990705)9:13<1757:SAIOCC>2.0.ZU;2-0
Abstract
We have discovered a new series of potent conformationally constrained MMP Inhibitors that are selective for MMP-13 over MMP-1. (C) 1999 Elsevier Scie nce Ltd. All rights reserved.